Disease modifying drugs in rheumatoid arthritis

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Bone mineral density changes during treatment of rheumatoid arthritis with disease-modifying-anti-rheumatic drugs

Background: Bone mineral density (BMD) changes during the course of rheumatoid arthritis (RA). The present study was designed to investigate the status of BMD in patients with RA treated with anti-rheumatic drugs. Methods: BMD at the femoral neck (FN-BMD) and lumbar spine (LS-BMD) were measured by dual energy x-ray absorptiometry (DXA) method using Norland densitometer. Disease activity (DA) wa...

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Corticosteroids as disease modifying drugs in rheumatoid arthritis treatment.

The current approach to treatment of RA includes early and aggressive treatment with routine monitoring of outcomes to give patients the best chance of decreasing disease activity as much as possible, with low disease activity and remission being a realistic goal for many patients. In this quest, DMARDs, especially MTX, are the anchor treatment, and low dose prednisone should also be considered...

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Evidence for early disease-modifying drugs in rheumatoid arthritis

Some research evidence supports early aggressive treatment of rheumatoid arthritis (RA) using combination therapy with two or more disease modifying anti-rheumatic drugs (DMARDs) plus steroids, or even DMARDs plus an anti-TNF. By contrast, conservatively delayed DMARD monotherapy, given after non-steroidal anti-inflammatory drugs have failed, has been criticised. However, recent long-term studi...

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bone mineral density changes during treatment of rheumatoid arthritis with disease-modifying-anti-rheumatic drugs

background: bone mineral density (bmd) changes during the course of rheumatoid arthritis (ra). the present study was designed to investigate the status of bmd in patients with ra treated with anti-rheumatic drugs. methods: bmd at the femoral neck (fn-bmd) and lumbar spine (ls-bmd) were measured by dual energy x-ray absorptiometry (dxa) method using norland densitometer. disease activity (da) wa...

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ژورنال

عنوان ژورنال: BMJ

سال: 1997

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.314.7083.766